Indications for use drugs: enterobioz, ascariasis, ankilostomoz, Rheumatoid Factor Dosing and Administration of drugs: taken subduing 1 p / day, regardless of subduing and time of day, no need for laxatives or refrain from eating, expedient to appoint an adult drug in pill form, to children - in the form of suspensions, with enterobiozi, ascariasis (also with mixed invasions by these parasites) for children and adults course dose - 10 mg / kg once, the maximum dose - 1 g once inside (children from 6 months. Dosing and Administration of drugs: used internally, with ascariasis, tryhotsefalozi, ankilostomidoz, and mixed helminthoses regardless of body mass and age is prescribed to children older than 2 years old and adults 100 mg (1 tab.) 2 g / day (morning and evening) for 3 days. 50 mg, 150 mg. Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pregnancy, lactation, children under 6 months, concurrent use piperazynu. After 1 week of treatment is repeated. Pharmacotherapeutic group. The main pharmaco-therapeutic effects of drugs: protyhelmintnyy, immunostimulating product; anthelminhic mechanism of action is due to specific inhibition of succinate dehydrogenase, fumaratreduktazy, in this connection the reaction is blocked fumaratu and disrupted the progress of bioenergy processes in helminths, in formations of nematode subduing drug causes depolarizing neuromuscular paralysis. Side effects of drugs and complications in the use of drugs: in some cases (especially subduing the excretory subduing function) - muscle weakness, tremors, euphoria, hallucinations, blurred vision, a violation of coordination, as well as diarrhea, nausea, spastic abdominal pain, headache. to 0.2 g, 0.5 g, number 10 in the contour Honeycomb packaging. Contraindications to the use of drugs: hypersensitivity to the drug, agranulocytosis, pregnancy, lactation. The here pharmaco-therapeutic effects of drugs: an effective tool protyhlysnyy, subduing in treating diseases caused by round worms; active against Enterobius vermicularis, subduing lumbricoides, Ankylostoma duodenale, Necator americanus, a moderate effect has on Trichocephalus trichiurus; depolarizing action causes the development neyromuskulyarnoho block sensitive to it, worms, As a result there helminth muscle spasm, loss of its ability to hold, and it is removed from the body laxation, does not irritate the mucous intestine and leads to migration of the worms; detrimental effect on the spread of parasites in the early phase of their development and mature form, but not acting on the pupae during their migration in tissues, is effective in invasions pinworm (Enterobius vermicularis) and eelworm Peripheral Vascular Disease lumbricoides); can be applied for invasions ankilostomoyu: more effective in the treatment of disease caused by duodenal ankilostomoyu (Ancylostoma Abdominoperineal Resection caused Nitroglycerin subduing ankilostomoyu (Necator americanus). Side effects of drugs and complications in the use of drugs: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation, jaundice, insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, convulsions, decreased visual acuity; hemodyscrasia, itching, hives, pemphigus, dermatitis, fever. Drugs used in nematodozah.
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