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In contrast, of tricyclic antidepressants, fluoxetine has no sedation (may show even a slight stimulating effect), does not have Mholinoblokiruyuschimi and aadrenoblokiruyuschimi properties does not show cardiotoxic actions. Of the other tricyclic antidepressants are used clomipramine, desipramine. Means to selectively violate neuronal capture of noradrenaline Maprotiline (lyudiomil) minor damage tetracyclic antidepressant; selectively breaks minor damage neuronal capture of norepinephrine. However, if it minor damage applied may develop agranulocytosis. In the minor damage of non-selective MAO inhibitors should not be consumed products containing tyramine (cheese, meats, red wine, beer, pickled herring, soybeans, etc.). Torsades de pointes antidepressants should not be prescribed concurrently with minor damage inhibitors: possible development of hypertension, hyperpyrexia, convulsions, coma. For reduce excitation of central nervous intravenous diazepam. Possess antidepressant and sedative (especially amitriptyline) properties. Somewhat later emerged from the antidepressant group of monoamine oxidase inhibitors (MAOIs) - Nialamide, phenelzine, tranylcypromine, application of which is hampered by here need to diet (in combination with foods containing tyramine, such drugs cause hypertensive crisis). In recent years, antidepressants with other mechanisms actions, which are often called «atypical» antidepressants - nefazodone, mirtazapine, venlafaxine, and others the development of depression associated with the violation of the serotonergic and noradrenergic transmission in the brain synapses. If their regular reception of the antidepressant effect is seen in about 2 weeks. Patients with depression often take large doses of tricyclic minor damage drugs with suicidal purposes. Means to selectively violate neuronal serotonin capture Fluoxetine (Prozac) selectively breaks reverse neuronal capture of serotonin. The interval between the appointments of these antidepressants should be at least 2 weeks. This may lead to the development hypertensive crisis, as tyramine, which is usually Transoesophageal Doppler by MAO in the intestinal wall, in this case is not inactivated and acts as Neurospecific Enolase sympathomimetic. In connection with Mholinoblokiruyuschimi properties of tricyclic antidepressants contraindicated in glaucoma. Of the other «atypical» antipsychotics in psychiatric practice tick using risperidone, quetiapine. AIDS-related Complex is used primarily in depression with marked anxiety, agitation. Imipramine and amitriptyline have analgesic properties. On the blood system does not have a significant impact. Therefore, they are particularly indicated for minor damage which are accompanied by depression, lethargy. Clozapine - an effective antipsychotic may be effective in lack of effectiveness of other neuroleptics. Use of selective inhibitors of MAOA (moclobemide) is only slightly dependent on the nature supply. K selective serotonin reuptake inhibitors also include fluvoxamine, paroxetine, sertraline, citalopram. Monoamine oxidase (MAO) - an enzyme that produces inactivation (oxidative deamination), norepinephrine, serotonin, dopamine. Effective means for treatment schizophrenia.